In December 2019, a novel coronavirus, now named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novel CoV-2, but has subsequently been officially named SARS-CoV-2 by the WHO. On January 30, 2020, the WHO declared the outbreak of SARS-CoV-2 a Public Health Emergency of International Concern. Compared with the SARS-CoV that caused an outbreak of SARS in 2003, SARS-CoV-2 has a stronger transmission capacity. The rapid increase in confirmed cases makes the prevention and control of coronavirus disease 2019 (COVID-19) extremely serious. The virus is transmittable between humans and has caused pandemic worldwide. The number of death tolls continues to rise, and a large number of countries have been forced to do social distancing and lockdown. Lack of targeted therapy continues to be a problem. Studies have shown that SARS-CoV-2 infects host cells through angiotensin-converting enzyme 2 receptors, leading to COVID-19-related pneumonia, while also causing acute myocardial injury and chronic damage to the cardiovascular system. The gastrointestinal symptoms include abdominal pain, diarrhea, appetite loss, nausea, and vomiting, and neurologic symptoms include cerebrovascular strokes and encephalitis.

Background: Dental anxiety is one of the key reasons behind patient's unwillingness to seek dental treatment. It is quite challenging to manage and hinders the ability of dentist to deliver the best dental treatment. Many nonpharmacological therapies have been introduced to manage dental anxiety, and music therapy is one of such therapy. Aim and Objective: The aim of the study was to assess whether music has an effect in reducing anxiety levels in patients during routine dental procedures. This was a randomized control experimental study. Materials and Methods: In this study, 100 patients (mean age: 32 years) from the Outpatient Department of SDKSDC, Nagpur, India, who volunteered and consented to participate in the study were included in the study. Inclusion criteria were patients who require only routine dental treatment. Participants were randomly assigned into two groups: the control group (n = 50) and the study group (n = 50). Patients in the study group were exposed to relaxing, low tempo music through headphones during routine dental procedures which include scaling and restorative procedure. Both groups were assessed using Corah's dental anxiety scale, blood pressure, and heart rate, before and after treatment. Results: Music therapy was effective in reducing anxiety during the procedures; participants in the study group had significantly lower anxiety scores compared to the control group. Conclusion: Music therapy has been shown to be an effective nonpharmacological approach to reduce dental anxiety among patients during routine dental procedures.

Context: Dental caries is the most common type of dental problem known to mankind, and the bacterial species-Streptococcus mutans (S.mutans) is known to initiate it, thus playing a significant role in dental caries formation. Theobromine in dark chocolate and probiotics are known for anticariogenic and antibacterial properties. Aims: The aim of this study is to find the effectiveness of white chocolate, dark chocolate, and probiotic-infused dark chocolate against S. mutans. Subjects and Methods: Blood-infused Mueller–Hinton agar was prepared with three wells. Twenty grams of chocolate were dispersed in each well. Chlorhexidine and saline were used as positive and negative control. The agar plate was then streaked with S. mutans. These prepared culture media was then allowed to incubate at 37°C for a time period of about 24 h under sterile environment. Finally, the diameters of the zone of inhibition were measured using the Hi Antibiotic Zone Scale. ANOVA and Tukey's post hoc test were used for statistical. Statistical Analysis Used: ANOVA and Tukey's post hoc test were used for statistical. Results: On comparison, probiotic-infused dark chocolate shows the greatest zone of inhibition (16.83 ± 1.329) followed by chlorhexidine (15.18 ± 1.458) which is then followed by dark chocolate (11.33 ± 1.751) and white chocolate (7.17 ± 1.835), and finally normal saline which showed no zone of inhibition. On overall evaluation using ANOVA, the statistically significant difference was found out (P < 0.001). Intergroup comparison was performed using Tukey's post hoc test, whose P < 0.001 thus being statistically significant. Conclusion: Among all the different kinds of chocolates used in the study, probiotic-infused dark chocolate showed the greatest anti-microbial activity against S. mutans.